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Clinically-Driven Skincare

Where Clinical Science Meets Modern Skincare

Advanced formulations designed to strengthen the skin barrier, refine texture, and support long-term skin health.

Our trusted certifications and badges:

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Clinically-Driven Skincare

Where Clinical Science Meets Modern Skincare

Advanced formulations designed to strengthen the skin barrier, refine texture, and support long-term skin health.

Our trusted certifications and badges:

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Hydrate • Protect • Renew

Learn More About Trilipiderm

Hydrate • Protect • Renew

Learn More About Trilipiderm

Skin Cell Science

Plant-based formulas, cutting-edge skin cell science

Environmental Impact

Our philanthropic approach to supporting our planet

Our Story

Welcome to our home: Jackson Hole, WY

Skin Cell Science

At the core of many Trilipiderm formulas is our proprietary Medasynnian™ Lipid Complex.

This advanced lipid system is precisely formulated with Meadowfoam seed oil and Abyssinian oil—two highly stable, antioxidant-rich lipids selected for their exceptional skin compatibility and performance.

Together, they help calm visible irritation, reinforce the skin barrier, and deliver deep, lasting hydration for skin that looks balanced, resilient, and refined.

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Environmental Impact

Supporting the planet & our local community

We support environmental stewardship through eco-friendly production and packaging practices: our packaging is transitioning to 100% eco-friendly solutions, as we work towards becoming a zero-waste company.

We also make a point to partner with local and national causes to provide funding and sponsorships that promote our mission to protect our communities and our planet at large.

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Our Story

We are experts in dry skin

Trilipiderm was born in Jackson Hole, WY, one of the driest climates in the country. The Teton mountains have inspired our formulations; we source our ingredients from the heart of nature itself.

Our approach to hydration is unique, fueled by the functional botanicals of the American West. And after 15 years in the skincare industry, we have confidently refined the highest quality formulas on the market, providing you with luxurious skincare that produces the results your skin craves.

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85% Repurchase Rate

Our products are used again and again

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Eco-Friendly

Our mission: promoting skin health through environmental responsibility

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Satisfaction Guarantee

Love your results or get your money back

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Made in USA

All of our products are proudly made in the United States

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